When you’re LIVING WITH ANTI-AChR ANTIBODY-POSITIVE GENERALIZED MYASTHENIA GRAVIS (gMG)
A part of your immune system called complement plays an important role in your disease
Complement causes damage
Complement is a part of your immune system and normally helps to protect against certain types of infections. However, for people with anti-acetylcholine receptor (AChR) antibody-positive gMG, complement is activated by anti-AChR antibodies, which trigger complement to damage the area where your nerves and muscles meet.
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Complement is activated when anti-AChR antibodies bind to the AChR on your muscles
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Damage occurs when complement attacks the surface of the muscle
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This damage prevents the muscle from receiving messages/signals from your nerves
Hear from a neurologist
Thomas Pitts, MD, discusses complement and explains how a normally helpful part of the immune system causes damage in people with anti-AChR antibody-positive gMG.
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Recognize the symptoms